Genetic Services Have Value beyond BRCA1/2 Testing
نویسندگان
چکیده
منابع مشابه
On marker-assisted prediction of genetic value: beyond the ridge.
Marked-assisted genetic improvement of agricultural species exploits statistical dependencies in the joint distribution of marker genotypes and quantitative traits. An issue is how molecular (e.g., dense marker maps) and phenotypic information (e.g., some measure of yield in plants) is to be used for predicting the genetic value of candidates for selection. Multiple regression, selection index ...
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This article presents a tentative grounded theory, which can provide some explanation of variation in behaviour around predictive genetic testing (PGT) for Hereditary Non-Polyposis Colorectal Cancer (HNPCC), based on interviews with individuals (n = 55) from families with a clinical diagnosis of HNPCC, 12 of whom were followed through the PGT protocol. The theory is built around a core category...
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BACKGROUND Several companies offer direct-to-consumer (DTC) genetic testing to evaluate ancestry and wellness. Massive-scale testing of thousands of single-nucleotide polymorphisms (SNPs) is not error free, and such errors could translate into misclassification of risk and produce a false sense of security or unnecessary anxiety in an individual. We evaluated 3 DTC services and a genomics servi...
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To the Editor: The corneal deposits seen in heterozygote granular corneal dystrophy type 2 (GCD2) can be observed in individuals with variable appearances.1 When the deposits are small and at times undetectable, only genetic analysis is effective for the confirmative diagnosis. Many refractive surgeons have adopted genetic testing prior to refractive surgery to verify that their patients are fr...
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The extraordinary success of physicists to find simple laws that explain many phenomena is beguiling. With the exception of quantum mechanics, it suggests a deterministic world in which theories are right or wrong, and the world is simple. However, attempts to apply such thinking to other phenomena have not been so successful. Individually and collectively we face many situations dominated by u...
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ژورنال
عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention
سال: 2009
ISSN: 1055-9965,1538-7755
DOI: 10.1158/1055-9965.epi-08-1087